Thyme oil for pgd2 inhibition, do you think it works?
Yeah but seems to be a cox 2 inhibitor. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789773/
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Laurent Descamps
baldie
Eri sheme
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I've been on fin/min for 6 mth didn't notice much. Taking castor (oral & topical) for 2 weeks and seeing tiny baby hairs grow in vast numbers across crown. Should I stop fin/min?
You should definitely at least stay on fin. Not sure about minox, if you think it helps then you should stick with it as well.
Swiss, a question about your Kerastase Densifique shampoo. One of the listed ingredients is salicylic acid, a COX inhibitor....what's up with that? I thought you were very adamant about not using any COX inhibitors in the protocol...Thoughts?
I don't actually see in the ingredients on mine. Maybe it differs from country to country? Thanks for the warning though
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Where/how do you get VPA and Sulfasalazine?
I got VPA from a groupbuy but you can buy the pills and dissolve em in ethanol. Sulfa from inhouse.
Peppermint oil inhibits PGE2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262447/
Noted. Thank you!
Forgot to mention this in my last question. Sorry. I have PMS sulfasalazine EC. Is it the same thing as regular sulfasalazine?
Feel free to ask more questions if you have them, no worries. I just don't always have the time to get to them unfortunately. Anyway yes those are fine. EC means enteric coated which is actually the preferred form.
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Eri sheme
How would I apply LiCi all over my scalp? I'm a diffuse thinner.
I wouldn't say licl is needed in diffusers since it's mostly intended for truly bald scalps.
If you want to use it you can either dissolve it in water or ethanol, both works.
If you want to use it you can either dissolve it in water or ethanol, both works.
halo. so what is the corelation between reduced blood flow, lets say due to stress, and androgen receptors and PGs? lets say you restrict the blood flow to the scalp of a woman, and her hair starts to shrink and eventually falls, does it still have any connection with DHT?
Well if you have truly, severely reduced blood flow the tissue won't get enough nourishment anymore and it starts to die. That's not only the case with hair of course. No it's not related to DHT. But in general the "blood flow" theories are not correct. It only affects your hair in extreme cases.
Hi Swiss, In the sheets that you posted you refer to endogenous PGE2 production. What is the difference with exogenous? Does it have to do with the topical/oral dose?
Endogenous means produced by your own body. Exogenous means you supply it from an outside source.
With PGE2 endogenous is your natural pge2 levels, exogenous means applying pge2 powder that you bought from somewhere.
With PGE2 endogenous is your natural pge2 levels, exogenous means applying pge2 powder that you bought from somewhere.
I'm using a local anesthesic before wounding, is that a problem?
Nah that is fine man
Did somebody start using st John's Wort or Gingko in your forum? Topical or oral?
Uh yes I do actually believe I saw some threads about oral use, long time ago though.
So castor oil is not only a pge2 agonist but also a ptgds inhibitor?
A bit far fetched. There is anecdotal evidence but it's likely only very lightly doing that. We need more data.
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I thought I read somewhere that you mentioned to not take 2% ketoconazole shampoo if you're on the protocol.. is this correct ? Also what is your methodology /portions when mixing Castor oil and penetrating agents when being applied topically to the scalp? Thanks!
Keto can inhibit endogenous pge2 synthesis. If you are on sulfasalazine it would be a step back.
I use 30% dmso 70% castor. Some other use ethanol, some put it in their minox. What we do know now is that you NEED a penetration enhancer. I read a study recently that showed almost no absorption from topical castor alone.
I use 30% dmso 70% castor. Some other use ethanol, some put it in their minox. What we do know now is that you NEED a penetration enhancer. I read a study recently that showed almost no absorption from topical castor alone.
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Héctor Miguel Durán
Do you use any of the possible future treatments?
Not yet no. I am trying to get my hands on the pulmagen formula so we can get a cheaper and stronger alternative to seti.
Hi, I just wondering how you would advise someone to go about getting an invite to the PHG forum?
Contact user "tubzy".
you should be already familiar with the recent news involving Jak-stats inhibitors. What do think about them, may they work for common hair loss as well, in your opinion?
Yes I believe they have potential but a trial of tofacitinib by us last year has not worked. I believe it's most likely because unlike in AA scalp you have abnormal pgd2 levels in MPB scalp. Likely you'd need the combo for us "normal" baldies.
just sent you a question about buying seti from you..
Again I don't sell anything
I'd really like to try seti and maybe pge2 together. I've been trying to be invited, sent you some mails but have no response. If you could provide the price for me, you can get your profit.. I'd send you the money so as you could buy it for me and send them to me, if it is at all possible..
No man I can't I'm sorry. For one thing I don't need money and second I am not selling anything nor am I involved that much in the groupbuy. I'm just a moderator. Price was/is 260$ per 100mg. Try to contact user tubzy for an invite. Good luck, hope to see you soon.
Does low level lasers increase PGE2?
No lasers are a scam. Unless you want to remove hair, they work for that. :D
Ive never had any positive effect only further recession from minox, im 20 and a 3 year user and added finasteride last year should i just quit minox?
If you are CERTAIN that you did not have any growth from minox then yeah you should quit it. It ages your skin and it's not very healthy (even just topically) anyway. Stay on castor while you quit minox that should help your shed a bit. And you likely will shed.
I also never had any positive effect from Minox either. Lack of sulfurtransferase in us two guys.
I also never had any positive effect from Minox either. Lack of sulfurtransferase in us two guys.
they don't sell dermapen anymore. fda banned it. why
Are you sure? It's still in the shop here. Also fuck the FDA bunch of cunts.
http://shop.owndoc.com/product-list.php?Derminator-pg1-cid61.html
http://shop.owndoc.com/product-list.php?Derminator-pg1-cid61.html
Do you think that the so called "mpb itch" is due to too much pgd2 in the scalp?
Not really pgd2 itself no but it is faaaaaar down the cascade. Itch itself is caused by Nppb which can get triggered from heavy inflammation (such as pgd2).
I'm willing to give you 60K in 6 month, if you could take a NW6 and turn him into a NW2. I'm dead serious.
Give me a lab and unlimited access to all the substances I need and I'll do it for free. I'm dead serious.
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Alex
About Castor oil, I put ethanol on the temples and then apply castor oil and all the other stuff, Stemox, Minox. Is this correct?
No man you mix the ethanol into the castor oil first lol
Hi Swiss, I was a little confused by an earlier answer about dut: "Be warned though that you will shed more hair than normal for up to a year. If you can't accept your hair looking like shit during that time then don't use it." I haven't heard this before, was gonna start dut. Can you elaborate?
All anti androgens will first make you shed unless you are already using another anti androgen. It's commong knowledge. With Fin and Dut there is an acclimation phase for up to one year where you will shed and your hair might look even worse.
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